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Systems Biology


Fabrication and characterization of schottky gate poly(3-alkylthiophene) planar field-effect transistors

Fabrication and characterization of schottky gate poly(3-alkylthiophene) planar field-effect transistors

Brightness-Based Selection and Edge Detection-Based Enhancement Separation Algorithm for Low-Resolution Metal Transfer Images

Brightness-Based Selection and Edge Detection-Based Enhancement Separation Algorithm for Low-Resolution Metal Transfer Images

Protein-tyrosine phosphatases and cancer

Tyrosine phosphorylation is an important signalling mechanism in eukaryotic cells. In cancer, oncogenic activation of tyrosine kinases is a common feature, and…

Characterization of an imatinib-sensitive subset of high-grade human glioma cultures

Characterization of an imatinib-sensitive subset of high-grade human glioma cultures

Expression of DEP-1, a receptor-like protein-tyrosine-phosphatase, is enhanced with increasing cell density

cDNA encoding a receptor-like protein-tyrosine-phosphatase (PTP) termed DEP-1 was isolated from a HeLa cell library. The cDNA predicts an enzyme consisting of an…

Protein tyrosine phosphatases: regulatory mechanisms

Protein tyrosine phosphatases: regulatory mechanisms

Dynamic changes in the expression of DEP1 and other PDGF receptor-antagonizing PTPs during onset and termination of neointima formation

Growth factor-dependent tissue remodel- ing, such as restenosis, is believed to be predominantly regulated by changes in expression of receptor-tyrosine- kinases…

Laser-Assisted Cell Microdissection Using the PALM System

Laser-assisted microdissection has enabled the collection of morphologically defined cell populations from a tissue section. The PALM Robot MicroBeam laser…

A digest on the role of the tumor microenvironment in gastrointestinal cancers

Experimental studies and analyses of clinical material have convincingly demonstrated that tumor formation and progression occurs through a concerted action of…
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