Art

SUPPLEMENTARY ONLINE DATA Structure-function relationships in Escherichia coli adenylate cyclase

Description
SUPPLEMENTARY ONLINE DATA Structure-function relationships in Escherichia coli adenylate cyclase
Categories
Published
of 3
0
Categories
Published
All materials on our website are shared by users. If you have any questions about copyright issues, please report us to resolve them. We are always happy to assist you.
Share
Transcript
  Biochem. J. (2008)  415 , 449–454 (Printed in Great Britain) doi:10.1042/BJ20080350 SUPPLEMENTARY ONLINE DATA Structure–function relationships in  Escherichia coli   adenylate cyclase J¨urgen U. LINDER 1 Department of Pharmacology, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10065, U.S.A. 1 email jul2015@med.cornell.edu c  The Authors Journal compilation  c  2008 Biochemical Society www.biochemj.org    B   i  o  c   h  e  m   i  c  a   l   J  o  u  r  n  a   l  J.U. Linder Figure S1 Alignment of catalytic domains of 26 class I ACs in the range of residues 1–412 of the  E. coli   AC The 20 invariant or highly conserved functional residues targeted in the present study are shaded in black, invariant hydrophobic residues are shaded in grey. A bold line denotes the stretchhomologous with the pol β  nucleotidyltransferase superfamily [1]. Arrowheads mark the 12 residues identified as essential for catalysis. Residue numbering is on the right. E. coli,  Escherichia coli  ; Y. entero.,  Yersinia enterocolitica  ; V. chol.,  Vibrio cholerae  ; P. lumin.,  Photorhabdus luminescens  ; P. mirab.,  Proteus mirabilis  ; P. profun.,  Photobacterium profundum  ; A. hydrop.,  Aeromonas hydrophila  ; HTCC2143,  γ  -proteobacterium HTCC2143; P. ingrah.,  Psychromonas ingrahamii  ; A. pleuro.,  Actinobacillus pleuropneumoniae  ; Moritella,  Moritella   sp. PE36; M. succin.,  Mannheimia succiniciproducens  ; P. multoc.,  Pasteurella multocida  ; H. influ.,  Haemophilus influenzae  ; P. aerug.,  Pseudomonas aeruginosa  ; P. fluor.,  Pseudomonas fluorescens  ; Oceanobac.,  Oceanobacter   sp.RED65; H. cheju.,  Hahella chejuensis  ; Reinekea,  Reinekea   sp. MED297; S. degrad.,  Saccharophagus degradans  ; M. algico.,  Marinobacter algicola  ; S. frigid.,  Shewanella frigidimarina  ; S. oneid., Shewanella oneidensis  ; Alteromon.,  Alteromonas macleodii  ; MLMS1,  δ -proteobacterium MLMS-1; S. acidop.,  Syntrophus aciditrophicus  . c  The Authors Journal compilation  c  2008 Biochemical Society  Mechanism of  Escherichia coli   adenylate cyclase REFERENCES 1 Aravind, L. and Koonin, E. V. (1999) DNA polymerase  β -like nucleotidyltransferasesuperfamily: identification of three new families, classification and evolutionary history.Nucleic Acids Res.  27 , 1609–1618Received 15 February 2008/8 July 2008; accepted 11 July 2008Published as BJ Immediate Publication 11 July 2008, doi:10.1042/BJ20080350 c  The Authors Journal compilation  c  2008 Biochemical Society
Search
Tags
Related Search
We Need Your Support
Thank you for visiting our website and your interest in our free products and services. We are nonprofit website to share and download documents. To the running of this website, we need your help to support us.

Thanks to everyone for your continued support.

No, Thanks
SAVE OUR EARTH

We need your sign to support Project to invent "SMART AND CONTROLLABLE REFLECTIVE BALLOONS" to cover the Sun and Save Our Earth.

More details...

Sign Now!

We are very appreciated for your Prompt Action!

x